Peptides for mood

A melanocortin receptor agonist that enhances sexual desire and arousal in both men and women by acting centrally via the nervous system.

• Increased sexual desire and libido
• Enhanced arousal in men and women
• Acts via CNS — works regardless of hormonal status

Glycoprotein hormone produced during pregnancy. Mimics luteinizing hormone (LH), stimulating Leydig cells in the testes to produce testosterone and maintain testicular volume. Commonly co-administered with TRT to preserve fertility and prevent testicular atrophy, or used as a post-cycle/restart bridge.

• Testicular size preservation on TRT
• Maintains intratesticular testosterone
• Fertility preservation during exogenous testosterone use

Testosterone replacement therapy using a long-acting ester for stable hormone levels.

• Restored testosterone levels
• Improved energy and vitality
• Increased muscle mass and strength

A 28-amino-acid synthetic copy of a naturally occurring thymic peptide. Acts as an immune-system modulator (not a growth-hormone or anabolic peptide) by influencing T-cell maturation and innate immunity. Approved abroad as Zadaxin in 35+ countries for chronic hepatitis B and as an adjuvant in oncology — not FDA-approved in the US for general use. Typically cycled 6–12 weeks.

• Restores and modulates T-cell function
• Enhances vaccine response
• Supports immune resilience in immunocompromised states

A nine-amino-acid neuropeptide explored in research as an intranasal spray for social cognition, anxiety, and bonding effects. This entry reflects research-protocol intranasal microdosing only — distinct from obstetric IV oxytocin used during labor.

• May enhance affective empathy and social engagement
• Reduces self-reported social anxiety in some trials
• Studied as adjunct to exposure therapy

A synthetic decapeptide identical to native GnRH that triggers pituitary LH and FSH release, downstream stimulating endogenous testosterone and spermatogenesis. Used adjunctively in TRT to preserve testicular function and in hypogonadotropic hypogonadism via pulsatile dosing.

• Maintains testicular size during TRT
• Stimulates pituitary LH and FSH release
• Supports endogenous testosterone in HPG axis

A synthetic tripeptide (Glu-Asp-Arg) from Khavinson's bioregulator program at the St. Petersburg Institute of Bioregulation. Animal studies report reduced ROS in cerebellar granule and PC12 cells, plus improved cognitive outcomes in prenatal hyperhomocysteinemia and Alzheimer's mouse models.

• Reduces ROS in neuronal cells (preclinical)
• Neuroprotective in oxidative-stress models
• Improved offspring cognition in prenatal stress models

An orally bioavailable, blood-brain-barrier-penetrant hexanoyl-modified analog of angiotensin IV that potentiates the hepatocyte growth factor (HGF) / c-Met system. Preclinical work reports synaptogenesis at picomolar concentrations and reversal of scopolamine-induced cognitive deficits in rodents.

• Activates HGF/c-Met synaptogenic pathway (preclinical)
• Crosses the blood-brain barrier
• Induces hippocampal spinogenesis at picomolar doses

A 28-amino-acid neuropeptide signaling through VPAC1/VPAC2 receptors. Established anti-inflammatory and immunomodulatory effects across innate and adaptive immunity. Used clinically off-label as an intranasal preparation in chronic inflammatory response syndrome (CIRS) protocols.

• Suppresses pro-inflammatory cytokine production
• Induces regulatory T-cell phenotypes
• Studied for sepsis, RA, Crohn's, MS (preclinical)