Apple Health Outcome
12 compoundsin Regimen’s catalog are configured to track sleep duration via Apple Health. Each one shows the dose range, listed benefits, and every outcome it’s set up to monitor. Tap through to plan a dose with the free reconstitution calculator.
Total sleep duration is the simplest objective sleep metric — the sum of all stages from sleep onset to final wake. Apple Watch derives it from heart rate variability, motion, and breathing rate. Average adult totals fall between 7 and 9 hours; less than 6 is correlated with cardiometabolic risk across large epidemiological cohorts.
GH secretagogues such as CJC-1295/ipamorelin and MK-677 do not consistently increase total sleep duration in trial data — they more reliably shift sleep architecture toward more deep and REM sleep within the same total time. The subjective experience often described as "feeling rested in less time" reflects this architectural shift rather than a duration change.
For users whose primary issue is short sleep duration (rather than poor-quality sleep), peptides are typically not the first-line intervention. Behavioral changes — fixed bedtime, no screens, magnesium, addressing sleep apnea — produce larger duration gains than any peptide protocol.
12 compounds
GHRH / GHRP Combination
A synergistic growth hormone releasing combination for body composition, sleep, and recovery.
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GHRH (1-29) Analog
Synthetic analog of the first 29 amino acids of growth hormone–releasing hormone. Stimulates the pituitary to release endogenous GH in pulses, preserving the natural feedback loop and avoiding suppressed pituitary axis seen with exogenous HGH.
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Recombinant Human Growth Hormone
Recombinant DNA-derived 191-amino-acid growth hormone identical to endogenous human somatropin. FDA-approved for clinical GH deficiency (adult and pediatric); used off-label for body composition, recovery, and anti-aging. Direct hormone replacement — bypasses the pituitary axis (unlike Sermorelin/Tesamorelin).
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Lonapegsomatropin (TransCon hGH)
Skytrofa is a once-weekly, long-acting growth hormone for children with growth hormone deficiency (GHD). Lonapegsomatropin is a prodrug that slowly releases somatropin (hGH) over 7 days, providing stable GH levels with a single weekly injection instead of daily shots.
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Ghrelin Receptor GH Secretagogue
A synthetic hexapeptide that binds the ghrelin/GHS-R1a receptor to stimulate pulsatile growth hormone release from the anterior pituitary. Researched for GH deficiency, cachexia, and tissue-protective effects; also a potent appetite stimulant.
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Oral Ghrelin Mimetic / GH Secretagogue
An orally bioavailable, non-peptide ghrelin receptor agonist that produces sustained increases in GH and IGF-1 with once-daily dosing. Taken as a capsule — no reconstitution needed. Studied for sarcopenia, GH deficiency, and recovery support.
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Next-gen Ghrelin Receptor Agonist (research)
A research-grade non-peptide ghrelin receptor (GHS-R1a) agonist developed as a successor to MK-677. Vendor and analog modeling describe higher receptor affinity and longer half-life, but human clinical data are not yet published.
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Trial data on GH secretagogues shows architectural shifts (more deep and REM sleep) rather than longer total sleep. Some users do report falling asleep faster and sleeping later, which can produce a small total-duration increase. The effect size is modest compared with behavioral sleep interventions.
Apple Watch sleep tracking has been validated against polysomnography with reasonable accuracy for total duration (±15 minutes is typical) but with lower accuracy for stage classification. The trend over weeks is more reliable than any single night. Regimen reads the validated Apple Health values directly rather than recomputing.
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